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Textbook of Clinical ­Gastroenterology and ­Hepatology
By C. J. Hawkey (Edited by), Jaime Bosch (Edited by), Joel E. Richter, Guadalupe Garcia-Tsao (Edited by)

Rating
Format
Hardback, 1272 pages
Published
United Kingdom, 1 May 2012

Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.


Professor Christopher Hawkey is Professor of Gastroenterology at Nottingham University and Co-director of Nottingham University's Institute of Clinical Research, and President Elect of the British Society of Gastroenterology 2009. Professor Jaime Bosch is Professor of Medicine, and Senior Consultant Hepatologist and Chief at the Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic-Idibaps, University of Barcelona and Centro de Investigación Biomédica de Enfermedades Hepáticas y Digestivas (Ciberehd), Barcelona, Spain. Guadalupe Garcia-Tsao, MD is Professor of Medicine, Department of Internal Medicine, Section of Digestive Diseases at Yale University School of Medicine. Professor Francis Chan is Professor of Medicine and Therapeutics at The Chinese University of Hong Kong (CUHK) and an honorary consultant physician at the Prince of Wales Hospital (PWH).


List of contributors, x Preface, xxv Part 1: Symptoms, Syndromes, and Scenarios Discomfort above the diaphragm Section 2: Disorders of the Small and Large Bowel Food, nutrition and malabsorption Section 3: Diseases of the Pancreas and Biliary Tract Pancreas Section 4: Liver Disease Section 5: Diseases of Multiple Organ Systems Section 6: Abdominal Wall and Cavity Part 3: Primer of Diagnostic Methods Endoscopic imaging Part 4: Primer of Treatments Index, 1191

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Product Description

Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.


Professor Christopher Hawkey is Professor of Gastroenterology at Nottingham University and Co-director of Nottingham University's Institute of Clinical Research, and President Elect of the British Society of Gastroenterology 2009. Professor Jaime Bosch is Professor of Medicine, and Senior Consultant Hepatologist and Chief at the Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic-Idibaps, University of Barcelona and Centro de Investigación Biomédica de Enfermedades Hepáticas y Digestivas (Ciberehd), Barcelona, Spain. Guadalupe Garcia-Tsao, MD is Professor of Medicine, Department of Internal Medicine, Section of Digestive Diseases at Yale University School of Medicine. Professor Francis Chan is Professor of Medicine and Therapeutics at The Chinese University of Hong Kong (CUHK) and an honorary consultant physician at the Prince of Wales Hospital (PWH).


List of contributors, x Preface, xxv Part 1: Symptoms, Syndromes, and Scenarios Discomfort above the diaphragm Section 2: Disorders of the Small and Large Bowel Food, nutrition and malabsorption Section 3: Diseases of the Pancreas and Biliary Tract Pancreas Section 4: Liver Disease Section 5: Diseases of Multiple Organ Systems Section 6: Abdominal Wall and Cavity Part 3: Primer of Diagnostic Methods Endoscopic imaging Part 4: Primer of Treatments Index, 1191

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Product Details
EAN
9781405191821
ISBN
1405191821
Age Range
Other Information
Illustrated
Dimensions
27.9 x 22.1 x 5.3 centimeters (2.64 kg)

Table of Contents

List of contributors, x


Preface, xxv


Part 1: Symptoms, Syndromes, and Scenarios Discomfort above
the diaphragm


1 Heartburn and noncardiac chest pain, 3

Tiberiu Hershcovici and Ronnie Fass


2 Dysphagia and odynophagia, 11

Stacey R. Zavala and Philip O. Katz


Discomfort below the diaphragm


3 Chronic or recurrent abdominal pain, 16

Ayman Koteish and Anthony N. Kalloo


4 Dyspepsia: ulcer and non-ulcer/bloating and early
satiety/belching and rumination, 22

Alexander C. Ford and Paul Moayyedi


5 Nausea and vomiting, 26

Jan Tack


Disorders of defecation


6 Diarrhea, 32

Matthew R. Banks and Michael J. G. Farthing


7 Fecal incontinence, 43

Ashok Attaluri and Satish S. C. Rao


8 Rectal bleeding, 47

Benjamin Krevsky


9 Anorectal pain and pruritusani, 51

Steven D. Wexner and Giovanna M. da Silva


Generalized ill health


10 Functional gastrointestinal disease, 54

C. J. Hawkey, Jaime Bosch, Joel E. Richter, Guadalupe
Garcia-Tsao, and Francis K. L. Chan


11 Anorexia nervosa and bulimia nervosa, 61

Tomas J. Silber


12 Weight loss, 68

Arvey I. Rogers, Hendrikus S. Vanderveldt and Amar R.
Deshpande


13 Gastrointestinal causes of anemia and occult bleeding,
73

Kevin A. Ghassemi, Dennis M. Jensen and Rome Jutabha


28 Benign esophageal strictures and caustic esophageal injury,
194

Timothy T. Nostrant


Esophageal: malignant and pre-malignant


29 Barrett?s esophagus, 197

Neil Gupta and Prateek Sharma


30 Esophageal cancer, 204

Tamas A. Gonda and Charles J. Lightdale


Upper gastrointestinal infections


31 Infections of the esophagus and stomach, 214

George B. McDonald


Gastroduodenal: benign


32 Peptic ulcer, 219

C. J. Hawkey and John C. Atherton


33 Gastritis, 234

Richard H. Lash and Robert M. Genta


Gastroduodenal: malignant and pre-malignant


34 Adenocarcinoma (gastric cancer and miscellaneous malignancy),
248

Dai-ming Fan and Kai-chun Wu


35 Gastric lymphoma, 254

Andrea Grin and Runjan Chetty


Motility disorders


36 Esophageal motility disorders, 258

Peter J. Kahrilas


37 Gastric motility disorders, 265

Jan Tack


Section 2: Disorders of the Small and Large Bowel Food,
nutrition and malabsorption


38 Food allergy and intolerance, 272

Stephan C. Bischoff and Katrin Feuser


39 Maldigestion and malabsorption, 279

Arvey I. Rogers and Ryan D. Madanick


40 Celiac disease, 288

Daniel A. Leffler, Andrés Cárdenas and Ciarán P.
Kelly


41 Short bowel syndrome, 299

Christian S. Jackson and Alan L. Buchman


42 Small intestinal bacterial overgrowth, 305

Ahmed Abu Shanab, Rodrigo M. Quera and Eamonn M. M.
Quigley


43 Bile acid malabsorption, 311

Linda Wedlake and Jervoise Andreyev


44 Protein-losing disorders of the gastrointestinal tract,
318

Simon Murch


Intestinal infections and infestations


45 Infective diarrhea, 324

Michael J. G. Farthing and Anna Casburn-Jones


46 Travelers? diarrhea, 338

Andrew W. DuPont and Herbert L. DuPont


47 Abdominal tuberculosis, 342

Bhupinder Anand


48 Parasites, 349

John Croese


Inflammatory bowel disease


49 Ulcerative colitis, 355

Fergus Shanahan


50 Crohn?s disease, 372

Séverine Vermeire, Gert Van Assche and Paul
Rutgeerts


51 Indeterminate colitis, 394

Stephan R. Targan and C. J. Hawkey


52 Microscopic colitis, 399

Frank Hoentjen, Chris Mulder and Gerd Bouma


53 Eosinophilic disorders of the gastrointestinal tract,
406

Jon A. Vanderhoof and Rosemary J. Young


54 Pseudomembranous colitis, 412

Tanya M. Monaghan and Yashwant R. Mahida


55 Ischemia/ischemic colitis, 417

Aliya G. Hasan and Joel S. Levine


Malignant tumors


56 Small bowel tumours, 421

Matthew P. Spinn and Sushovan Guha


57 Biology and genetics of colorectal cancer and polyps and
polyposis, 428

Ajay Goel and Christian Arnold


58 Colorectal cancer: screening and surveillance, 438

Austin G. Acheson and John H. Scholefield


59 Colorectal cancer: a multidisciplinary approach, 444

Rachel S. Midgley, Haitham M. Al-Salama, A. Merrie, N.
Mortensen, and David J. Kerr


Motility disorders


60 Obstruction and volvulus, 455

Rakesh Bhardwaj and Michael C. Parker


61 Constipation and constipation syndromes, 462

Adil E. Bharucha and Madhusudan Grover


62 Irritable bowel syndrome, 472

Robin Spiller


63 Diverticular disease of the colon, 482

Anish A. Sheth and Martin H. Floch


64 Megacolon and pseudo-obstruction, 488

Eamonn M. M. Quigley


Other disorders of the small and large bowel


65 Splanchnic vascular disorders, 493

J. Hajo van Bockel, Robert H. Geelkerken and Jeroen J.
Kolkman


66 Drug-induced damage to the small and large intestine,
498

Ingvar Bjarnason, Zeino Zeino and Guy Sisson


67 Acute appendicitis, 505

John Simpson and David J. Humes


Anorectal diseases


68 Anorectal diseases, 511

Steven D. Wexner and Giovanna M. da Silva


Section 3: Diseases of the Pancreas and Biliary Tract
Pancreas


69 Acute pancreatitis, 518

Georgios Papachristou, Vijay Singh and David C. Whitcomb


70 Chronic pancreatitis, 525

Pascal O. Berberat, Güralp O. Ceyhan, Zilvinas Dambrauskas,
Markus W. Büchler, and Helmut Friess


71 Pancreatic exocrine tumors, 533

Paula Ghaneh and John P. Neoptolemos


72 Cysts and pseudocysts of the pancreas, 546

Brian G. Turner and William R. Brugge


73 Development and miscellaneous abnormalities, 552

Erica Makin and Mark Davenport


Biliary tract


74 Cholelithiasis, choledocholithiasis, and cholecystitis,
557

Franz Ludwig Dumoulin and Tilman Sauerbruch


75 Sphincter of Oddi dysfunction, 567

Dana C. Moffatt, Stuart Sherman and Evan L. Fogel


76 Primary sclerosing cholangitis, 573

Sombat Treeprasertsuk and Keith D. Lindor


77 Cholangiocarcinoma, 580

Konstantinos N. Lazaridis and Gregory J. Gores


Malformations


78 Congenital abnormalities of the biliary tract, 586

Daniel Dhumeaux, Elie Serge Zafrani, Daniel Cherqui, and Alain
Luciani


Section 4: Liver Disease


Infections


79 Acute viral hepatitis, 593

Amer Skopic and Maria H. Sjogren


80 Chronic hepatitis B, 603

Tarik Asselah, Olivier Lada, Rami Moucari, and Patrick
Marcellin


81 Chronic viral hepatitis C, 610

Xavier Forns and Jose M. Sánchez-Tapias


82 Chronic viral hepatitis D, 618

Patrizia Farci and Maria Eliana Lai


83 Liver worms, 623

Donald P. McManus


84 Liver protozoa, 630

David Kershenobich, Guillermo Robles-Diaz and Juan Miguel Abdo
Francis


85 Bacterial and fungal infections of the liver, 633

Simon Rushbrook and Alexander Gimson


86 Primary biliary cirrhosis, 638

Raoul Poupon


Autoimmune and related disorders


87 Autoimmune hepatitis and overlap syndromes, 642

Heike Bantel, Kinan Rifai and Michael P. Manns


Genetic, metabolic and iatrogenic liver diseases


88 Alcoholic liver diseases, 649

Jennifer T. Wells and Michael R. Lucey


89 Nonalcoholic fatty liver disease, 658

Arthur J. McCullough and Srinivasan Dasarathy


90 Hemochromatosis, 675

Antonello Pietrangelo


91 Alpha-1-antitrypsin deficiency, 683

Feras T. Alissa and David H. Perlmutter


92 Wilson disease, 689

Peter Ferenci


93 Drug prescription in liver disease, 695

Guido Stirnimann and Jürg Reichen


94 Genetic and metabolic liver diseases in childhood, 700

Giorgina Mieli-Vergani and Richard Thompson


95 Disturbances of bilirubin metabolism, 706

Cristina Bellarosa and Claudio Tiribelli


Cirrhosis of the liver and its complications


96 Polycystic liver diseases, 713

Luca Fabris, Catherine McCrann and Mario Strazzabosco


97 Cirrhosis of the liver, 719

Gennaro D?Amico and Giuseppe Malizia


98 Portal hypertension, 728

Juan Carlos García-Pagán, Roberto J. Groszmann and
Jaime Bosch


99 Ascites and hepatorenal syndrome, 737

Andrés Cárdenas and Pere Ginès


100 Spontaneous bacterial peritonitis, 745

Guadalupe Garcia-Tsao


101 Hepatopulmonary syndrome and portopulmonary hypertension,
751

Rajan Kochar and Michael B. Fallon


102 Hepatic encephalopathy, 757

Thomas A. Brown and Kevin D. Mullen


103 Acute liver failure, 766

John G. O?Grady and Julia Wendon


Other liver diseases


104 Tumors of the liver, 773

Alejandro Forner, Carlos Rodríguez de Lope, María
Reig, and Jordi Bruix


105 Vascular disorders of the liver, 786

Dominique-Charles Valla


106 Granulomas of the liver, 793

Miquel Bruguera Cortada and Rosa Miquel Morera


107 Liver diseases and pregnancy, 799

J. Eileen Hay


Liver transplantation


108 Liver transplantation: indications and selection of
candidates and immediate complications, 805

Patrick S. Kamath and John J. Poterucha


109 Long-term management of recurrent primary liver disease,
813

Kiran Bambha and Norah A. Terrault


Section 5: Diseases of Multiple Organ Systems


110 Collagen vascular and vasculitic disorders, 831

Ulf Müller-Ladner and Jürgen Schölmerich


111 Systemic disease and the gastrointestinal tract, 839

Paul J. Fortun


112 Pancreatic endocrine tumors, 844

Robert T. Jensen


113 The carcinoid syndrome, 858

Eva Tiensuu Janson and Kjell Öberg


114 AIDS and the gut, 865

C. Mel Wilcox


115 Graft-versus-host disease, 873

George B. McDonald


116 Radiation and other physicochemical injury, 879

Keith Leiper and Andrew R. Moore


117 Systemic amyloidosis, 886

Prayman T. Sattianayagam and Philip N. Hawkins


118 Foreign bodies, 893

Lisa Swize and Patrick R. Pfau


119 Porphyria, 898

Jean-Charles Deybach and Hervé Puy


120 The hereditary recurrent fevers, 908

Elizabeth Drewe


Section 6: Abdominal Wall and Cavity


121 Abscesses and other intra-abdominal diseases, 913

Juliane Bingener, Melanie L. Richards and Kenneth R.
Sirinek


122 Hernia, 919

Cindy Matsen and Leigh Neumayer


Part 3: Primer of Diagnostic Methods Endoscopic
imaging


123 Upper gastrointestinal endoscopy and mucosal biopsy,
927

Jayan Mannath and Krish Ragunath


124 Lower gastrointestinal endoscopy and biopsy, 936

Jerome D. Waye


125 Endoscopic ultrasonography, 943

V. Raman Muthusamy and Kenneth J. Chang


126 Diagnostic and interventional endoscopic retrograde
cholangiopancreatography, 951

George J. M. Webster and Stephen P. Pereira


127 Enteroscopy (double-balloon), 961

Tomonori Yano and Hironori Yamamoto


128 Capsule endoscopy, 969

Christina A. Tennyson and Blair S. Lewis


129 Confocal endomicroscopy, 975

Martin Goetz and Ralf Kiesslich


130 Self-propelled colonoscopy, 983

Menachem Moshkowitz and Nadir Arber Percutaneous imaging


131 Percutaneous ultrasound, 989

Winnie C. W. Chu and Vivian Y. F. Leung


132 Barium radiology, 1000

Simon A. Jackson and Bruce M. Fox


133 Computed tomography, 1006

Karin Herrmann and Pablo R. Ros


134 Magnetic resonance imaging, 1014

Luca Marciani, Robin C. Spiller, Penny A. Gowland, and Peter D.
Thurley


135 Magnetic resonance cholangiopancreatography, 1021

V. Anik Sahni and Koenraad J. Mortele


136 Virtual colonoscopy, 1027

Abraham H. Dachman, Ila Sethi and Philippe Lefere


137 Positron emission tomography, 1035

Sebastian Obrzut and Michael S. Kipper


138 Non-invasive liver assessment, 1042

M. Beaugrand


Functional testing


139 Gastrointestinal motility testing, 1046

Priyanka Sachdeva and Henry P. Parkman


140 Measurement of portal pressure, 1054

Annalisa Berzigotti and Juan G. Abraldes


Tissue testing


141 Liver biopsy, 1060

Cristina Ripoll and Rafael Bañares


142 Optimal tissue sampling: the pathologist?s
perspective, 1066

Richard H. Lash, Shari L. Taylor and Robert M. Genta


Part 4: Primer of Treatments


Medical treatments


143 Drug prescription in liver disease, 1077

Guido Stirnimann and Jürg Reichen


144 Nutritional assessment and support, 1082

T. E. Bowling


Therapeutic endoscopy


145 Variceal ligation, sclerotherapy, and other hemostatic
techniques for varices and other lesions, 1092

Louis-Michel Wong Kee Song


146 Non-variceal upper gastrointestinal bleeding, 1103

Majid Almadi and Alan Barkun


147 Photodynamic therapy in the gastrointestinal tract,
1111

Masoud Panjehpour and Bergein F. Overholt


148 Percutaneous endoscopic gastrostomy and jejunostomy,
1120

Jeffrey L. Ponsky and Benjamin K. Poulose


149 Endoscopic techniques of removing early gastrointestinal
neoplams, 1126

Haruhiro Inoue and Hitomi Minami


150 Dilation and stenting of the gastrointestinal tract,
1134

Lucio Petruzziello, Michele Marchese and Guido
Costamagna


151 NOTES, 1142

D. Nageshwar Reddy, G. V. Rao and Magnus J. Mansard


Percutaneous therapy


152 The transjugular intrahepatic portosystemic shunt (TIPS),
1147

Christophe Bureau, Philippe Otal and Jean-Pierre Vinel


153 Interventional radiology, 1153

Simon Chun-Ho Yu and Joyce Wai Yi Hui


154 Paracentesis, 1158

Andrea De Gottardi, Chong-Meng Yeo and Guadalupe
Garcia-Tsao


A synopsis of surgical operations


155 Liver operations, 1163

J. Michael Henderson and Michael D. Johnson


156 Gastrointestinal operations, 1174

Robert J. C. Steele


157 Minimally invasive surgery, 1182

Todd A. Ponsky, Arjun Khosla and Jeffrey L. Ponsky


Index, 1191

About the Author

Professor Christopher Hawkey is Professor ofGastroenterology at Nottingham University and Co-director ofNottingham University s Institute of Clinical Research, andPresident Elect of the British Society of Gastroenterology 2009. Professor Jaime Bosch is Professor of Medicine, andSenior Consultant Hepatologist and Chief at the Hepatic HemodynamicLaboratory, Liver Unit, Hospital Clinic-Idibaps, University ofBarcelona and Centro de Investigacion Biomedica deEnfermedades Hepaticas y Digestivas (Ciberehd), Barcelona,Spain. Guadalupe Garcia-Tsao, MD is Professor of Medicine,Department of Internal Medicine, Section of Digestive Diseases atYale University School of Medicine. Professor Francis Chan is Professor of Medicine andTherapeutics at The Chinese University of Hong Kong (CUHK) and anhonorary consultant physician at the Prince of Wales Hospital(PWH).

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