Cerebral Reorganization of Function After Brain Damage integrates basic research on neuroplasticity and clinical research on reorganization of function after brain injury, with a view toward translating the findings to rehabilitation. Historical foundations of research on neuroplasticity are
presented to provide a perspective on recent findings. Leading investigators synthesize their work with results from other laboratories to provide a current update on neuroanatomic features that enhance neuroplasticity and provide a substrate for reorganization of function. The capacity for recovery
from brain injury associated with focal lesions as compared to diffuse cerebral insult is discussed. Interventions such as environmental enrichment and drugs to enhance reorganization of function after brain injury have been studied in animal models and in human studies. Methodologies to study
neuroplasticity are discussed including functional magnetic resonance imaging, neurophysiological measures, transcranial magnetic stimulation, and computational modeling. Implications of neuroplasticity research for innovations in rehabilitation of persons with brain injury are critically reviewed.
This text will be particularly appealing to neuropsychologists, neurologists, psychologists, neuroscientists, psychiatrists, speech scientists, and other health professionals engaged in rehabilitation-related research.
Cerebral Reorganization of Function After Brain Damage integrates basic research on neuroplasticity and clinical research on reorganization of function after brain injury, with a view toward translating the findings to rehabilitation. Historical foundations of research on neuroplasticity are
presented to provide a perspective on recent findings. Leading investigators synthesize their work with results from other laboratories to provide a current update on neuroanatomic features that enhance neuroplasticity and provide a substrate for reorganization of function. The capacity for recovery
from brain injury associated with focal lesions as compared to diffuse cerebral insult is discussed. Interventions such as environmental enrichment and drugs to enhance reorganization of function after brain injury have been studied in animal models and in human studies. Methodologies to study
neuroplasticity are discussed including functional magnetic resonance imaging, neurophysiological measures, transcranial magnetic stimulation, and computational modeling. Implications of neuroplasticity research for innovations in rehabilitation of persons with brain injury are critically reviewed.
This text will be particularly appealing to neuropsychologists, neurologists, psychologists, neuroscientists, psychiatrists, speech scientists, and other health professionals engaged in rehabilitation-related research.
Foreword byMary Ellen Cheung:
1: Arthur Benton and Daniel Tranel: Historical Notes on the
Reorganization of Function and Neuroplasticity
PART I: NEUROSCIENCE RESEARCH ON NEUROPLASTICITY AND REORGANIZATION
OF FUNCTION
2: Jocelyne Bachevalier and Ludise Malkova: Neuropsychological
Indices of Early Medical Temporal Lobe Dysfunction in Primates
3: Robert J. Hamm, Meredith D. Temple, Deanna L. Buck, S. Michelle
DeFord, and Candace L. Floyd: Cognitive Recovery from Traumatic
Brain injury: Results of Post-Traumatic Experimental
Interventions
4: E.R. Ergenzinger and T.P. Pons: Growth of New Connections and
Adult Reorganizational Plasticity in the Somatosensory System
5: Helen Barbas: Neuroanatomic Basis for Reorganization of Function
After Prefrontal Damage in Primates
6: Bryan Kolb and Ian Q. Whishaw: Reorganization of Function After
Cortical Lesions in Rodents
7: J. Xu and J.T. Wall: Rapid Reorganization of Subcortical and
Cortical Maps in Adult Primates
8: Timothy Schallert, Sondra Bland, J. Leigh Humm, Jennifer
Tillerson, Reuben Gonzales, Lawrence Williams, Jaroslaw Aronowski,
and James Grotta: Motor Rehabilitation, Use-related Neural Events,
and Reorganization of the Brain After Injury
9: Randolph J. Nudo, Scott Barbay, and Jeffrey A. Kleim: Role of
Neuroplasticity in Functional Recovery After Stroke
PART II DEVELOPMENTAL STUDIES OF NEUROPLASTICITY
10: Joan Stiles: Spatial Cognitive Development Following Pre- or
Perinatal Focal Brain Injury
11: Harvey S. Levin, James Song, Sandra B. Chapman, and Harriet
Harward: Neuroplasticity Following Traumatic Diffuse vs. Focal
Brain Injury in Children: Studies of Verbal Fluency
12: Göran Carlsson and Kenneth Hugdahl: Cerebral Reorganization in
Children With Congenital Hemiplegia: Evidence From Dichotic
Listening Test
13: L.J. Carr: Reorganization of Function After Brain Injury
PART III TECHNIQUES FOR STUDYING NEUROPLASTICITY IN HUMANS
14: Pauline A. Filipek: The Developmental Disorders: Does
Plasticity Play a Role?
15: Eric M. Wasserman, Leonardo G. Cohen, and Mark Hallett:
Transcranial Magnetic Stimulation as a Tool for Detecting Change in
the Organization of the Human Motor System After Central and
Peripheral Lesions
16: Timothy C. Rickard: Methodological Issues in fMRI Studies of
Plasticity Following Brain Injury
17: Randy L. Buckner and Steven E. Petersen: Neuroimaging of
Functional Recovery
18: James A. Reggia, Sharon Goodall, Ken Revett, and Eytan Ruppin:
Computational Modeling of the Cortical Response to Focal Damage
PART IV: SYNTHESIS AND IMPLICATIONS FOR REHABILITATION
19: Paul Bach-y-Rita: Conceputal Issues in Neuroplasticity and
Reorganization of Function After Brain Injury
"The purpose of this book is to provide an update of important
neuroplasticity research and to identify how this work can be
translated into practical gains in the clinical setting. This is an
important goal and is largely achieved."--anadian Journal of
Surgery, Vol. 44, No 2, April 2001
Journal of Nervous and Mental Disease
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